Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides.

Human genetics - 1 Sept 2005

Coon Hilary, Xin Yuanpei, Hopkins Paul N, Cawthon Richard M, Hasstedt Sandra J, Hunt Steven C

Abstract excerpt

Positive evidence has been reported for linkage and association between the upstream stimulatory factor 1 gene (USF1) and familial combined hyperlipidemia (FCHL). We genotyped the two most positive single-nucleotide polymorphisms (SNPs) (usf1s1: rs3737787 and usf1s2: rs2073658) from previous studies in a large family sample. This sample included 2,195 subjects in 87 Utah pedigrees ascertained for early death due...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age of Onset

Share to Cholesterol, LDL

Share to Coronary Artery Disease

Share to Hyperlipidemia, Familial Combined

Share to Hypertension

Share to Stroke

Share to Triglycerides

Share to Upstream Stimulatory Factors

Source

Identifiers

PMID: 15959806
DOI: 10.1007/s00439-005-1340-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides.PMID 15959806Read ↗

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).Semantic proximity Read ↗

The involvement of upstream stimulatory factor 1 in Dutch patients with familial combined hyperlipidemia.Semantic proximity Read ↗

USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.Semantic proximity Read ↗

Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.Semantic proximity Read ↗

Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: association study in 2000 Dutch Caucasians.Semantic proximity Read ↗

Association of USF1 and APOA5 polymorphisms with familial combined hyperlipidemia in an Italian population.Semantic proximity Read ↗

Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1.Semantic proximity Read ↗

Potential role of upstream stimulatory factor 1 gene variant in familial combined hyperlipidemia and related disorders.Semantic proximity Read ↗

Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II.Semantic proximity Read ↗

USF1 and dyslipidemias: converging evidence for a functional intronic variant.Semantic proximity Read ↗

Genetics of familial combined hyperlipidemiaSemantic proximity Read ↗

USF1 gene variants, cardiovascular risk, and mortality in European Americans: analysis of two US cohort studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.