Article
Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients.
Oncology reports - 1 Jul 2008
Georgieva Milka, Krasteva Maria, Angelova Elka, Ralchev Krassimir, Dimitrov Valentin, Bozhimirov Stanislav, Georgieva Elena, Berger Martin R
Abstract excerpt
Colorectal cancer patients may succumb to their disease because of local recurrence or formation of metastasis. To develop a prognostic tool for these fatal types of progression, 23 patients with colorectal carcinoma were included in this study for the detection at the time of surgery of the incidence of K-ras, B-raf and p53 mutations, the phosphorylation status of Erk and the expression of cystatin-like...
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