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Article

ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics.

World journal of surgical oncology - 29 Feb 2012

Levidou Georgia, Saetta Angelica A, Gigelou Fanie, Karlou Maria, Papanastasiou Polyanthi, Stamatelli Angeliki, Kavantzas Nikolaos, Michalopoulos Nikolaos V, Agrogiannis George, Patsouris Efstratios, Korkolopoulou Penelope

Abstract excerpt

BACKGROUND: Colorectal (CRC) carcinogenesis through various morphological stages has been linked to several genetic and epigenetic changes. The Raf/MEK/ERK (MAPK) signal transduction cascade is an important mediator of a number of cellular fates. METHODS: In this study, we investigated the presence of B-raf and K-ras mutations in 94 consecutive cases of primary colon adenocarcinoma in correlation with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22376079
DOI: 10.1186/1477-7819-10-47
PMCID: PMC3320554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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