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Article

Clinical-pathological correlation of K-Ras mutation and ERK phosphorylation in colorectal cancer.

Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jun 2012

Tai Cheng-Jeng, Chang Chun-Chao, Jiang Ming-Chung, Yeh Chung-Min, Su Tzu-Cheng, Wu Pei-Ru, Chen Chih-Jung, Yeh Kun-Tu, Lin Shu-Hui, Chen Hung-Chang

Abstract excerpt

The Ras-ERK pathway is frequently up-regulated in colorectal cancer. We analyzed the clinical-pathological correlation of K-Ras mutation and phospho-ERK expression in colorectal cancer. K-Ras mutations were detected in only 32.5% (41/126) of the colorectal cancer cases, while all cancers were positive for phospho-ERK staining. Colorectal cancer with wild-typeK-Ras and low phospho-ERK expression had a...

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PMID: 22864777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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