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Article

CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor.

Molecular and cellular biochemistry - 1 Sept 2008

Scaglioni P P, Yung T M, Choi S, Choi S C, Baldini C, Konstantinidou G, Pandolfi P P

Abstract excerpt

The PML tumor suppressor controls growth suppression, induction of apoptosis, and cellular senescence. PML loss occurs frequently in hematopoietic and solid tumors. PML loss often correlates with tumor progression. Casein kinase 2 (CK2) is a stress-activated serine/threonine protein kinase that i...

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Source

Identifiers

PMID: 18566754
DOI: 10.1007/s11010-008-9812-7

Genes

PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18566754-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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