Article
Heat shock enhances NGF-induced neurite elongation which is not mediated by Hsp25 in PC12 cells.
Brain research - 24 Jul 2008
Read Danielle E, Reed Herbert Kate, Gorman Adrienne M
Abstract excerpt
Neuronal differentiation and neurite outgrowth are key processes during development of the nervous system. Understanding the regulation of neurite outgrowth stimulated by neurotrophins is crucial to developing therapies to promote axon regeneration after injury or in neurodegenerative diseases. Treatment of PC12 cells with nerve growth factor (NGF) stimulates them to extend neurites and differentiate into a...
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