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Article

Genetic polymorphism at the glutathione S-transferase (GST) P1 locus is a breast cancer risk modifier.

International journal of cancer - 1 Feb 2001

Maugard C M, Charrier J, Pitard A, Campion L, Akande O, Pleasants L, Ali-Osman F

Abstract excerpt

The isolation of full-length cDNAs of naturally occurring GSTP1 gene variants, and the demonstration that these alleles are distributed in the normal population, have provided conclusive evidence that the human GSTP1 gene locus is polymorphic and that specific GSTP1 alleles may be associated with different risk for cancers or other diseases. Recent data have indicated that the different GSTP1 alleles encode...

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Source

Identifiers

PMID: 11169956
DOI: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1057>3.0.co;2-h

Genes

GSTP1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Genetic polymorphism at the glutathione S-transferase (GST) P1 locus is a breast cancer risk modifier.PMID 11169956Read ↗

A functional polymorphism in the promoter region of GSTM1 implies a complex role for GSTM1 in breast cancer.Semantic proximity Read ↗

GSTP1 methylation and polymorphism increase the risk of breast cancer and the effects of diet and lifestyle in breast cancer patientsSemantic proximity Read ↗

Glutathione S-transferase M1, T1, and P1 genotypes and breast cancer risk: a study in a Portuguese population.Semantic proximity Read ↗

GSTT1 and GSTP1 polymorphisms and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Association between polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer risk in a sample Iranian population.Semantic proximity Read ↗

Genetic polymorphisms in GSTM1, GSTP1, and GSTT1 and the risk for breast cancer: results from the Shanghai Breast Cancer Study and meta-analysis.Semantic proximity Read ↗

A meta-analysis of the association of glutathione S-transferase P1 gene polymorphism with the susceptibility of breast cancer.Semantic proximity Read ↗

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Polymorphisms of glutathione S-transferase genes (GSTM1, GSTP1 and GSTT1) and breast cancer susceptibility.Semantic proximity Read ↗

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