Article
Molecular cytogenetic anomalies and phenotype alterations in a newly established cell line from Wilms tumor with diffuse anaplasia.
Cancer genetics and cytogenetics - 1 Jul 2008
Faussillon Marine, Murakami Ichiro, Bichat Magalie, Telvi Louise, Jeanpierre Cécile, Nezelof Christian, Jaubert Francis, Gogusev Jean
Abstract excerpt
The novel continuous cell line WT-Pe.1 was established in vitro from Wilms tumor with histological features of diffuse anaplasia. The cultures grew as poorly differentiated epithelial-like cells with pleomorphic polygonal shapes and formation of typical monolayers. WT-Pe.1 cells were immunoreactive for cytokeratin, vimentin, laminin, villin, CD10, and CD24 proteins. Conventional cytogenetic analysis by...
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