High-risk blastemal Wilms tumor can be modeled by 3D spheroid cultures in vitro

Abstract excerpt

In vitro models represent a critical tool in cancer research to study tumor biology and to evaluate new treatment options. Unfortunately, there are no effective preclinical models available that represent Wilms tumor (WT) - the most common pediatric renal tumor. Especially the high-risk blastemal WT subtype is not represented by the few primary cell lines established until now. Here, we describe a new 3D approach...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Pluripotent Stem Cells Research
• Share to Renal and related cancers
• Share to Renal cell carcinoma treatment