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Article

High-resolution genomic profiling of an adult Wilms' tumor: evidence for a pathogenesis distinct from corresponding pediatric tumors.

Virchows Archiv : an international journal of pathology - 1 Nov 2011

Karlsson Jenny, Holmquist Mengelbier Linda, Elfving Peter, Gisselsson Nord David

Abstract excerpt

Wilms' tumor (WT), the most common kidney tumor among children, is characterized by a triphasic morphology consisting of blastemal, epithelial, and stromal components. Adult WT is a rare malignancy displaying similar histological features. We here present the first published high-resolution genomic analysis of a mixed-type adult WT. This revealed a more pronounced genetic complexity than usually observed in...

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Identifiers

PMID: 21947875
DOI: 10.1007/s00428-011-1148-0

Genes

FHIT
NEGR1
WWOX
ZFPM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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