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Article

Two molecular subgroups of Wilms' tumors with or without WT1 mutations.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2003

Schumacher Valérie, Schuhen Stefanie, Sonner Sandra, Weirich Angela, Leuschner Ivo, Harms Dieter, Licht Jonathan, Roberts Stefan, Royer-Pokora Brigitte

Abstract excerpt

PURPOSE: Wilms' tumors (WTs) exhibit more than one pattern of differentiation, each of which is associated with distinctive clinical features and treatment responses. Mutations in the WT1 gene are found predominantly in WTs with stromal histology. To better understand the biological and clinical features in different WTs, we have analyzed WTs with and without WT1 mutations for a set of parameters. EXPERIMENTAL...

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PMID: 12796362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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