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Article

Regulation of SRF/CArG-dependent gene transcription during chronic partial obstruction of murine small intestine.

Neurogastroenterology and motility - 1 Jul 2008

Chen J, Chen H, Sanders K M, Perrino B A

Abstract excerpt

Intestinal obstructions lead to a variety of motility disorders. Small intestine smooth muscles undergo dramatic phenotypic changes in response to obstruction, but the underlying molecular mechanisms are unknown. Using RT-PCR, ChIP, Re-ChIP, and Western blots, we examined the effect of small bowel mechanical obstruction on smooth muscle gene expression. Obstruction caused a transient hyperplasia, followed by a...

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Source

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Identifiers

PMID: 18557893
DOI: 10.1111/j.1365-2982.2008.01149.x
PMCID: PMC8320440

Genes

SRF
KLF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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