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Article

Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice.

Gastroenterology - 1 Aug 2008

He Wei-Qi, Peng Ya-Jing, Zhang Wen-Cheng, Lv Ning, Tang Jing, Chen Chen, Zhang Cheng-Hai, Gao Song, Chen Hua-Qun, Zhi Gang, Feil Robert, Kamm Kristine E, Stull James T, Gao Xiang, Zhu Min-Sheng

Abstract excerpt

BACKGROUND & AIMS: Smooth muscle is essential for maintaining homeostasis for many body functions and provides adaptive responses to stresses imposed by pathologic disorders. Identified cell signaling networks have defined many potential mechanisms for initiating smooth muscle contraction with or without myosin regulatory light chain (RLC) phosphorylation by myosin light chain kinase (MLCK). We generated...

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Source

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Identifiers

PMID: 18586037
DOI: 10.1053/j.gastro.2008.05.032
PMCID: PMC2648853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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