Article
The small GTPase ADP-ribosylation factor 6 negatively regulates dendritic spine formation.
FEBS letters - 19 Dec 2005
Miyazaki Hideyuki, Yamazaki Masakazu, Watanabe Hiroshi, Maehama Tomohiko, Yokozeki Takeaki, Kanaho Yasunori
Abstract excerpt
Actin cytoskeletal reorganization and membrane trafficking are important for spine morphogenesis. Here we investigated whether the small GTPase, ADP-ribosylation factor 6 (ARF6), which regulates actin dynamics and peripheral vesicular trafficking, is involved in the regulation of spine formation. The developmental expression pattern of ARF6 in mouse hippocampus was similar to that of the post-synaptic density...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
