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Article

Differential effects of COMT on gait and executive control in aging.

Neurobiology of aging - 1 Mar 2010

Holtzer R, Ozelius L, Xue X, Wang T, Lipton R B, Verghese J

Abstract excerpt

Walking speed is associated with attention and executive control processes subserved by the prefrontal cortex. Because polymorphisms in catechol-O-methyltransferase (COMT) influence these cognitive processes we hypothesized that the same polymorphisms may influence gait velocity. We examined the associations between the Val(158)Met polymorphism in COMT and gait velocity as well as attention and executive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18547681
DOI: 10.1016/j.neurobiolaging.2008.05.011
PMCID: PMC2821742

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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