Article
Cytokeratins 8 and 19 in the mouse placental development.
The Journal of cell biology - 30 Oct 2000
Tamai Y, Ishikawa T, Bösl M R, Mori M, Nozaki M, Baribault H, Oshima R G, Taketo M M
Abstract excerpt
To investigate the expression and biological roles of cytokeratin 19 (K19) in development and in adult tissues, we inactivated the mouse K19 gene (Krt1-19) by inserting a bacterial beta-galactosidase gene (lacZ) by homologous recombination in embryonic stem cells, and established germ line mutant mice. Both heterozygous and homozygous mutant mice were viable, fertile, and appeared normal. By 7.5-8.0 days post...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
