Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recent advances in the genetics of spastic paraplegias.

Current neurology and neuroscience reports - 1 May 2008

Stevanin Giovanni, Ruberg Merle, Brice Alexis

Abstract excerpt

Hereditary spastic paraplegias (HSPs) are genetically heterogeneous mendelian disorders characterized by weakness and spasticity in the lower limbs associated with additional neurologic signs in "complex" or "complicated" forms. Major advances have been made during the past two decades in our understanding of their molecular bases. The mapping of 34 genes (17 of which have been identified) involved in this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, X
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hereditary Neurological Disorders

Share to Neurogenetic and Muscular Disorders Research

Share to Neurological diseases and metabolism

Share to Paraplegia

Share to Phenotype

Source

Identifiers

PMID: 18541115
DOI: 10.1007/s11910-008-0032-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recent advances in the genetics of spastic paraplegias.PMID 18541115Read ↗

Hereditary spastic paraplegia: clinical-genetic characteristics and evolving molecular mechanisms.Semantic proximity Read ↗

Delving into the complexity of hereditary spastic paraplegias: how unexpected phenotypes and inheritance modes are revolutionizing their nosologySemantic proximity Read ↗

Hereditary spastic paraplegia.Semantic proximity Read ↗

Genetics of hereditary spastic paraplegias.Semantic proximity Read ↗

Insights into Clinical, Genetic, and Pathological Aspects of Hereditary Spastic Paraplegias: A Comprehensive OverviewSemantic proximity Read ↗

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms.Semantic proximity Read ↗

The genetics of hereditary spastic paraplegia and implications for drug therapy.Semantic proximity Read ↗

Clinical and genetic update of hereditary spastic paraparesis.Semantic proximity Read ↗

Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms.Semantic proximity Read ↗

Molecular aspects of hereditary spastic paraplegia.Semantic proximity Read ↗

Hereditary spastic paraplegia: Genetic heterogeneity and common pathways.Semantic proximity Read ↗

Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.