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Article

Clinical and genetic update of hereditary spastic paraparesis.

Revue neurologique - 1 May 2021

Lallemant-Dudek P, Durr A

Abstract excerpt

Hereditary spastic paraparesis is a group of inherited neurological diseases characterized by underlying wide genetic heterogeneity. It should be suspected if there is a positive familial history, a common genetic alteration (i.e. SPG4, the most overall frequent form), or association with other signs, such as cerebellar ataxia (i.e. SPG7), early cognitive impairment or even cognitive deficit (i.e. SPG11), or...

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Botulinum Toxin and Related Neurological Disorders
Genetic Association Studies
Hereditary Neurological Disorders
Mutation
Paraparesis, Spastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spastic Paraplegia, Hereditary

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PMID: 32807405
DOI: 10.1016/j.neurol.2020.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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