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Article

Molecular aspects of hereditary spastic paraplegia.

Experimental cell research - 1 Jul 2014

Noreau Anne, Dion Patrick A, Rouleau Guy A

Abstract excerpt

Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by progressive lower limbs spasticity and weakness. What was first thought to be a small group of rare Mendelian disorder has now become a large group that includes many complex syndromes. While large families with defined modes of inheritance were used for the initial HSP gene...

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Identifiers

PMID: 24631291
DOI: 10.1016/j.yexcr.2014.02.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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