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Article

Fibulin-1 is required for morphogenesis of neural crest-derived structures.

Developmental biology - 15 Jul 2008

Cooley Marion A, Kern Christine B, Fresco Victor M, Wessels Andy, Thompson Robert P, McQuinn Tim C, Twal Waleed O, Mjaatvedt Corey H, Drake Christopher J, Argraves W Scott

Abstract excerpt

Here we report that mouse embryos homozygous for a gene trap insertion in the fibulin-1 (Fbln1) gene are deficient in Fbln1 and exhibit cardiac ventricular wall thinning and ventricular septal defects with double outlet right ventricle or overriding aorta. Fbln1 nulls also display anomalies of ao...

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Source

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Identifiers

PMID: 18538758
DOI: 10.1016/j.ydbio.2008.04.029
PMCID: PMC2965525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18538758-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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