Article
Fgfr1 regulates patterning of the pharyngeal region.
Genes & development - 1 Jan 2003
Trokovic Nina, Trokovic Ras, Mai Petra, Partanen Juha
Abstract excerpt
Development of the pharyngeal region depends on the interaction and integration of different cell populations, including surface ectoderm, foregut endoderm, paraxial mesoderm, and neural crest. Mice homozygous for a hypomorphic allele of Fgfr1 have craniofacial defects, some of which appeared to result from a failure in the early development of the second branchial arch. A stream of neural crest cells was found...
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