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Article

Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans.

Current biology : CB - 24 Jun 2008

Kruisselbrink Evelien, Guryev Victor, Brouwer Karin, Pontier Daphne B, Cuppen Edwin, Tijsterman Marcel

Abstract excerpt

To safeguard genetic integrity, cells have evolved an accurate but not failsafe mechanism of DNA replication. Not all DNA sequences tolerate DNA replication equally well [1]. Also, genomic regions that impose structural barriers to the DNA replication fork are a potential source of genetic instab...

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Identifiers

PMID: 18538569
DOI: 10.1016/j.cub.2008.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18538569-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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