Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of genetic polymorphism of cytochrome P4502D6 with dextromethorphan oxidative metabolism in Chinese.

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2000

Cai W, Chen B, Tao X, Ling S, Zhang Y

Abstract excerpt

OBJECTIVE: To determine the genetic mechanism of dextromethorphan oxidative polymorphism in Chinese subjects. METHODS: CYP2D6 genotype was analyzed by polymerase chain reaction (PCR) and Hph I restriction fragment length polymorphism (RFLP) techniques in 119 healthy Chinese subjects. RESULTS: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cytochrome P-450 CYP2D6
Share to Dextromethorphan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Oxidation-Reduction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 10837520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10837520-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of genetic polymorphism of cytochrome P4502D6 with dextromethorphan oxidative metabolism in Chinese.PMID 10837520Read ↗

Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes.Semantic proximity Read ↗

Analysis of the CYP2D6 gene in relation to dextromethorphan O-demethylation capacity in a Japanese population.Semantic proximity Read ↗

Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans.Semantic proximity Read ↗

CYP2D6 genotype and phenotype relationship in South Indians.Semantic proximity Read ↗

Effects of the Chinese herbal formula "Zuojin Pill" on the pharmacokinetics of dextromethorphan in healthy Chinese volunteers with CYP2D6*10 genotype.Semantic proximity Read ↗

Identification and drug metabolic activity evaluation of 12 CYP2D6 allelic variants newly detected in the Chinese population.Semantic proximity Read ↗

Identification of CYP2D6 impaired functional alleles in Mexican Americans.Semantic proximity Read ↗

CYP2D6 phenotyping with dextromethorphan.Semantic proximity Read ↗

Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese.Semantic proximity Read ↗

Frequency of CYP2D6*10 and *14 alleles and their influence on the metabolic activity of CYP2D6 in a healthy Chinese population.Semantic proximity Read ↗

Comparison of two CYP2D6 genotyping methods and assessment of genotype-phenotype relationships.Semantic proximity Read ↗

Metabolic activity of dextromethorphan O-demethylation in healthy Japanese volunteers carrying duplicated CYP2D6 genes: duplicated allele of CYP2D6*10 does not increase CYP2D6 metabolic activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.