Article
Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT.
Proteins - 1 Dec 2008
Noskov Sergei Y
Abstract excerpt
The recently published X-ray structure of LeuT, a Na(+)/Cl(-)-dependent neurotransmitter transporter, has provided fresh impetus to efforts directed at understanding the molecular principles governing specific neurotransmitter transport. The combination of the LeuT crystal structure with the results of molecular simulations enables the functional data on specific binding and transport to be related to molecular...
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