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Article

Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site.

Nature - 23 Dec 2010

Piscitelli Chayne L, Krishnamurthy Harini, Gouaux Eric

Abstract excerpt

Neurotransmitter/sodium symporters (NSSs) couple the uptake of neurotransmitter with one or more sodium ions, removing neurotransmitter from the synaptic cleft. NSSs are essential to the function of chemical synapses, are associated with multiple neurological diseases and disorders, and are the t...

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Identifiers

PMID: 21179170
DOI: 10.1038/nature09581
PMCID: PMC3079577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21179170-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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