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Article

Properties of an inward-facing state of LeuT: conformational stability and substrate release.

Biophysical journal - 24 Mar 2015

Grouleff Julie, Søndergaard Siri, Koldsø Heidi, Schiøtt Birgit

Abstract excerpt

The leucine transporter (LeuT) is a bacterial homolog of the human monoamine transporters, which are important pharmaceutical targets. There are no high-resolution structures of the human transporters available; however, LeuT has been crystallized in several different conformational states. Recen...

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Identifiers

PMID: 25809252
DOI: 10.1016/j.bpj.2015.02.010
PMCID: PMC4375683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25809252-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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