Article
MCP-1 -2518 A/G single nucleotide polymorphism in Slovak patients with systemic sclerosis.
Mediators of inflammation - 1 Jan 2008
Navratilova Zdenka, Lukac Jozef, Mrazek Frantisek, Kriegova Eva, Bucova Maria, Bosak Vladimir, Petrek Martin
Abstract excerpt
Recent study in a group of German patients with SSc has implicated the SNP in the MCP-1 gene (-2518 A to G) as a factor of susceptibility to SSc. Reflecting the need for replication of genetic association studies, we investigated if this SNP is associated with SSc in another Caucasian population. MCP-1 -2518 A/G genotypes were determined using PCR-SSP in 46 SSc patients and in 449 healthy subjects, all unrelated...
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