Article
Interleukin 1alpha single-nucleotide polymorphism associated with systemic sclerosis.
The Journal of rheumatology - 1 Jan 2004
Hutyrová Beáta, Lukác Jozef, Bosák Vladimír, Buc Milan, du Bois Roland, Petrek Martin
Abstract excerpt
OBJECTIVE: In systemic sclerosis (SSc), constitutive expression of the proinflammatory and fibrogenic cytokine interleukin 1alpha (IL-1alpha) by dermal fibroblasts from the affected skin has been observed. We investigated the association of a single-nucleotide polymorphism at position -889 in the...
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