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Article

The MCP-1-2518 (A to G) single nucleotide polymorphism in Czech patients with pulmonary sarcoidosis: association with Löfgren's syndrome.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Mar 2007

Navratilova Zdenka, Mrazek Frantisek, Kriegova Eva, Hutyrova Beata, Kolek Vitezslav, du Bois Roland M, Petrek Martin

Abstract excerpt

BACKGROUND AND AIM: The chemokine Monocyte Chemoattractant Protein (MCP)-1/CCL2, a chemoattractant for mononuclear cells, has already been implicated in the pathogenesis of sarcoidosis. A single nucleotide polymorphism (SNP) located at the position -2518 (A to G) of the MCP-1 gene has been reported to alter production of the MCP-1 protein in vitro and ex vivo. The present study, therefore, explored a possible...

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Identifiers

PMID: 18069417

Genes

CCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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