Genetic variations of the bitter taste receptor TAS2R38 are associated with obesity and impact on single immune traits.

doi:10.1002/mnfr.201500804

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Article

Genetic variations of the bitter taste receptor TAS2R38 are associated with obesity and impact on single immune traits.

Molecular nutrition & food research - 1 Jul 2016

Ortega Francisco J, Agüera Zaida, Sabater Mònica, Moreno-Navarrete José M, Alonso-Ledesma Isabel, Xifra Gemma, Botas Patricia, Delgado Elías, Jimenez-Murcia Susana, Fernández-García José C, Tinahones Francisco J, Baños Rosa M, Botella Cristina, de la Torre Rafael, Frühbeck Gema, Rodrigüez Amaia, Estivill Xavier, Casanueva Felipe, Ricart Wifredo, Fernández-Aranda Fernando, Fernández-Real José M

Abstract excerpt

SCOPE: Changes in genetic variations affecting the taste receptor, type 2, member 38 (TAS2R38) may identify the interacting mechanism leading to obesity and potential associations with proteins partaking in innate immunity, such as surfactant protein D (SPD) and mannan-binding lectin (MBL). METHODS AND RESULTS: We evaluated haplotypes of the bitter-taste receptor TAS2R38 in an identification sample of 210 women...

Topics

Adolescent
Adult
Aged
Body Mass Index
Body Weight
Case-Control Studies
Cohort Studies
Female
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunity, Innate

Male

Mannose-Binding Lectin

Middle Aged

Obesity

Polymorphism, Single Nucleotide

Pulmonary Surfactant-Associated Protein D

Receptors, G-Protein-Coupled

Source

Open in PubMed

Identifiers

PMID: 27059147
DOI: 10.1002/mnfr.201500804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27059147-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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