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Article

Does genetic variation in a bitter taste receptor gene alter early smoking behaviours in adolescents and young adults?

Addiction (Abingdon, England) - 1 Jul 2022

Alsaafin Alaa, Chenoweth Meghan Jo-Ann, Sylvestre Marie-Pierre, O'Loughlin Jennifer, Tyndale Rachel Fynvola

Abstract excerpt

BACKGROUND AND AIMS: Variation in the TAS2R38 taste receptor gene alters the ability to taste bitter compounds. We tested whether TAS2R38 variation influences early smoking behaviours in adolescence, a critical period of acquisition when taste may influence the natural course of tobacco use. DESIGN AND PARTICIPANTS: Observational study (Nicotine Dependence in Teens [NDIT]). Cox proportional hazards models were...

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Identifiers

PMID: 35293057
DOI: 10.1111/add.15871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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