Article
The hangover gene negatively regulates bouton addition at the Drosophila neuromuscular junction.
Mechanisms of development - 1 Aug 2008
Schwenkert Isabel, Eltrop Rouven, Funk Natalja, Steinert Jörn R, Schuster Christoph M, Scholz Henrike
Abstract excerpt
The synaptic growth of neurons during the development and adult life of an animal is a very dynamic and highly regulated process. During larval development in Drosophila new boutons and branches are added at the glutamatergic neuromuscular junction (NMJ) until a balance between neuronal activity and morphological structures is reached. Analysis of several Drosophila mutants suggest that bouton number and size...
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