Article
Regulation of Fasciclin II and synaptic terminal development by the splicing factor beag.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 16 May 2012
Beck Erin S, Gasque Gabriel, Imlach Wendy L, Jiao Wei, Jiwon Choi Ben, Wu Pao-Shu, Kraushar Matthew L, McCabe Brian D
Abstract excerpt
Pre-mRNA alternative splicing is an important mechanism for the generation of synaptic protein diversity, but few factors governing this process have been identified. From a screen for Drosophila mutants with aberrant synaptic development, we identified beag, a mutant with fewer synaptic boutons and decreased neurotransmitter release. Beag encodes a spliceosomal protein similar to splicing factors in humans and...
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