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Article

The impact of CYP2D6 and CYP2C19 polymorphisms on suicidal behavior and substance abuse disorder among patients with schizophrenia: a retrospective study.

Therapeutic drug monitoring - 1 Jun 2008

Kobylecki Camilla J, Hansen Thomas, Timm Sally, Wang August, Jakobsen Klaus D, Sørensen Holger J, Rasmussen Henrik B, Werge Thomas

Abstract excerpt

Suicidal behavior and substance abuse are frequent phenomena among patients with schizophrenia and may be attributable in part to antipsychotic treatment failure. Individuals who carry functional variants of the CYP2D6 and CYP2C19 genes, shown to cause altered drug metabolism of psychoactive drug...

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Source

Identifiers

PMID: 18520596
DOI: 10.1097/FTD.0b013e31817721d6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18520596-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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