Article
Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population.
PloS one - 1 Jan 2012
Huo Ran, Tang Kefu, Wei Zhiyun, Shen Lu, Xiong Yuyu, Wu Xi, Niu Jiamin, Han Xia, Tian Zhengan, Yang Lun, Feng Guoyin, He Lin, Qin Shengying
Abstract excerpt
BACKGROUND: CYP2E1 is a member of the cytochrome P450 superfamily, which is involved in the metabolism and activation of both endobiotics and xenobiotics. The genetic polymorphisms of CYP2E1 gene (Chromosome 10q26.3, Accession Number NC_000010.10) are reported to be related to the development of several mental diseases and to be involved in the clinical efficacy of some psychiatric medications. We investigated...
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