Article
CYP2D6 gene deletion allele in patients with neuroleptic malignant syndrome: preliminary report.
Psychiatry and clinical neurosciences - 1 Aug 2005
Kato Daiji, Kawanishi Chiaki, Kishida Ikuko, Furuno Taku, Matsumura Takehiko, Hasegawa Hana, Suzuki Kyoko, Hirayasu Yoshio
Abstract excerpt
Neuroleptic malignant syndrome (NMS) is a potentially fatal adverse reaction to psychopharmacologic treatment. Reported herein are two NMS patients with schizophrenia who were found to possess a CYP2D6 gene deletion allele (CYP2D6*5). The deletion results in decreased CYP2D6 activity, possibly le...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
