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Article

White matter abnormalities in patients with obsessive-compulsive disorder and their first-degree relatives.

The American journal of psychiatry - 1 Oct 2008

Menzies Lara, Williams Guy B, Chamberlain Samuel R, Ooi Cinly, Fineberg Naomi, Suckling John, Sahakian Barbara J, Robbins Trevor W, Bullmore Ed T

Abstract excerpt

OBJECTIVE: Obsessive-compulsive disorder (OCD) is a common, heritable neuropsychiatric disorder, hypothetically underpinned by dysconnectivity of large-scale brain systems. The extent of white matter abnormalities in OCD is unknown, and the genetic basis of this disorder is poorly understood. The authors used diffusion tensor imaging, a magnetic resonance imaging technique, for examining white matter...

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Identifiers

PMID: 18519525
DOI: 10.1176/appi.ajp.2008.07101677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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