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Article

Endophenotypes of obsessive-compulsive disorder: rationale, evidence and future potential.

Expert review of neurotherapeutics - 1 Aug 2009

Chamberlain Samuel R, Menzies Lara

Abstract excerpt

Obsessive-compulsive disorder (OCD) is a heritable and debilitating neuropsychiatric condition. Attempts to delineate genetic contributions have met with limited success, and there is an ongoing search for intermediate trait or vulnerability markers rooted in the neurosciences. Such markers would be valuable for detecting people at risk of developing the condition, clarifying etiological factors and targeting...

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PMID: 19673603
DOI: 10.1586/ern.09.36

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