Article
Neurocognitive endophenotypes of obsessive-compulsive disorder.
Brain : a journal of neurology - 1 Dec 2007
Menzies Lara, Achard Sophie, Chamberlain Samuel R, Fineberg Naomi, Chen Chi-Hua, del Campo Natalia, Sahakian Barbara J, Robbins Trevor W, Bullmore Ed
Abstract excerpt
Endophenotypes (intermediate phenotypes) are objective, heritable, quantitative traits hypothesized to represent genetic risk for polygenic disorders at more biologically tractable levels than distal behavioural and clinical phenotypes. It is theorized that endophenotype models of disease will he...
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