Article
Executive dysfunctions in obsessive-compulsive patients and unaffected relatives: searching for a new intermediate phenotype.
Biological psychiatry - 15 Jun 2010
Cavedini Paolo, Zorzi Claudia, Piccinni Monica, Cavallini Maria Cristina, Bellodi Laura
Abstract excerpt
BACKGROUND: Evidence in literature suggests that neurocognitive deficits may represent suitable intermediate-phenotype candidates for the dissection of obsessive-compulsive disorder (OCD) genetic heterogeneity. The aim of this study was to search for possible OCD neurocognitive endophenotypes by assessing decision-making, planning, and mental flexibility profiles in OCD probands, healthy control subjects (HC),...
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