Article
Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives.
The American journal of psychiatry - 1 Aug 2013
Skudlarski Pawel, Schretlen David J, Thaker Gunvant K, Stevens Michael C, Keshavan Matcheri S, Sweeney John A, Tamminga Carol A, Clementz Brett A, O'Neil Kasey, Pearlson Godfrey D
Abstract excerpt
OBJECTIVE Both schizophrenia and bipolar disorder are hypothesized to involve disordered brain connectivity. Prior studies show low white matter integrity, measured with diffusion tensor imaging, for both disorders. The authors studied disease specificity and endophenotypic status of these abnormalities by examining patients and their unaffected relatives. METHOD The 513 participants included probands with...
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