Article
Association of cortical gyrification, white matter microstructure, and phenotypic profile in medication-naïve obsessive-compulsive disorder.
Psychological medicine - 1 Jun 2024
Li Jianyu, Cheng Jian, Yang Lei, Niu Qihui, Zhang Yuanchao, Palaniyappan Lena
Abstract excerpt
BACKGROUND: Obsessive-compulsive disorder (OCD) is thought to arise from dysconnectivity among interlinked brain regions resulting in a wide spectrum of clinical manifestations. Cortical gyrification, a key morphological feature of human cerebral cortex, has been considered associated with developmental connectivity in early life. Monitoring cortical gyrification alterations may provide new insights into the...
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