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Cortical and subcortical structural alterations in obsessive-compulsive disorder: relationships between morphology and clinical profiles in the Global OCD study

2025-07-23

Abstract excerpt

<h4>Background: </h4> The Global OCD consortium investigated cortical and subcortical alterations in obsessive-compulsive disorder (OCD) using T1-weighted MRI, focusing on the relationship between brain morphology and clinical phenotypes, illness duration, comorbidity and medication history. <h4>Methods:</h4> This preregistered study included 266 medication-free adults with OCD and 254 healthy controls. We analyze...

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Literature Corpus work
44b63ba3-e0ab-5042-a58d-e784793480c4
DOI
10.1101/2025.07.23.25332068
Open publication

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Cortical and subcortical structural alterations in obsessive-compulsive disorder: relationships between morphology and clinical profiles in the Global OCD studyDOI 10.1101/2025.07.23.25332068
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