Association between mu-opioid receptor-1 102T>C polymorphism and intermediate type 2 diabetes phenotypes: results from the Quebec Family Study (QFS).

doi:10.1111/j.1440-1681.2008.04972.x

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Article

Association between mu-opioid receptor-1 102T>C polymorphism and intermediate type 2 diabetes phenotypes: results from the Quebec Family Study (QFS).

Clinical and experimental pharmacology & physiology - 1 Sept 2008

Ruchat Stephanie-May, Girard Martine, Weisnagel S John, Bouchard Claude, Vohl Marie-Claude, Pérusse Louis

Abstract excerpt

It has been suggested recently that molecules expressed both in the pancreas and hypothalamus, such as mu-opioid receptor 1 (OPRM1), could form an integrated brain-liver system, which may sense glucose levels and therefore contribute to the development of type 2 diabetes mellitus (T2DM). In the present study, we tested associations between OPRM1 gene polymorphisms (rs1799971, 102T/C and rs0648007G/A) and indices...

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Identifiers

PMID: 18518884
DOI: 10.1111/j.1440-1681.2008.04972.x

Genes

OPRM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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