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Article

Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1

18 Apr 2013

Abstract excerpt

The β-glucan receptor Dectin-1 is a member of the C-type lectin family and functions as an innate pattern recognition receptor in antifungal immunity. In both mouse and man, Dectin-1 has been found to play an essential role in controlling infections with Candida albicans, a normally commensal fungus in man which can cause superficial mucocutaneous infections as well as life-threatening invasive diseases. Here,...

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PMID: 23637604
DOI: 10.1371/journal.ppat.1003315

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