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Candida albicans Infection of Caenorhabditis elegans Induces Antifungal Immune Defenses

23 Jun 2011

Abstract excerpt

Candida albicans yeast cells are found in the intestine of most humans, yet this opportunist can invade host tissues and cause life-threatening infections in susceptible individuals. To better understand the host factors that underlie susceptibility to candidiasis, we developed a new model to study antifungal innate immunity. We demonstrate that the yeast form of C. albicans establishes an intestinal infection in...

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PMID: 21731485
DOI: 10.1371/journal.ppat.1002074

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