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HIV Genetic Diversity and Drug Resistance

2 Feb 2010

Abstract excerpt

Most of the current knowledge on antiretroviral (ARV) drug development and resistance is based on the study of subtype B of HIV-1, which only accounts for 10% of the worldwide HIV infections. Cumulative evidence has emerged that different HIV types, groups and subtypes harbor distinct biological properties, including the response and susceptibility to ARV. Recent laboratory and clinical data highlighting such...

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PMID: 21994646
DOI: 10.3390/v2020503

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