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Article

Characterization of chondroitin sulfate lyase ABC from Bacteroides thetaiotaomicron WAL2926.

Biochemistry - 24 Jun 2008

Shaya David, Hahn Bum-Soo, Park Nam Young, Sim Joon-Soo, Kim Yeong Shik, Cygler Miroslaw

Abstract excerpt

Chondroitin sulfate ABC lyase (ChonABC) is an enzyme with broad specificity that depolymerizes via beta-elimination chondroitin sulfate (CS) and dermatan sulfate (DS) glycosaminoglycans (GAGs). ChonABC eliminates the glycosidic bond of its GAG substrates on the nonreducing end of their uronic acid component. This lyase possesses the unusual ability to act on both epimers of uronic acid, either glucuronic acid...

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PMID: 18512954
DOI: 10.1021/bi800353g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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