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Article

Biochemical characterization of the chondroitinase ABC I active site.

The Biochemical journal - 1 Sept 2005

Prabhakar Vikas, Raman Rahul, Capila Ishan, Bosques Carlos J, Pojasek Kevin, Sasisekharan Ram

Abstract excerpt

cABC I (chondroitinase ABC I) from Proteus vulgaris is a GalAG (galactosaminoglycan) depolymerizing lyase that cleaves its substrates at the glycosidic bond via beta-elimination. cABC I cleaves a particularly broad range of GalAG substrates, including CS (chondroitin sulphate), DS (dermatan sulphate) and hyaluronic acid. We recently cloned and recombinantly expressed cABC I in Escherichia coli, and completed a...

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PMID: 16108757
DOI: 10.1042/BJ20050532
PMCID: PMC1198919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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