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Article

Structural and functional analysis of a glycoside hydrolase family 97 enzyme from Bacteroides thetaiotaomicron.

The Journal of biological chemistry - 26 Dec 2008

Kitamura Momoyo, Okuyama Masayuki, Tanzawa Fumiko, Mori Haruhide, Kitago Yu, Watanabe Nobuhisa, Kimura Atsuo, Tanaka Isao, Yao Min

Abstract excerpt

SusB, an 84-kDa alpha-glucoside hydrolase involved in the starch utilization system (sus) of Bacteroides thetaiotaomicron, belongs to glycoside hydrolase (GH) family 97. We have determined the enzymatic characteristics and the crystal structures in free and acarbose-bound form at 1.6A resolution. SusB hydrolyzes the alpha-glucosidic linkage, with inversion of anomeric configuration liberating the beta-anomer of...

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Identifiers

PMID: 18981178
DOI: 10.1074/jbc.M806115200
PMCID: PMC2662298

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Source receipt: pubmed, retrieved 7 Sept 2026.

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